4E-T-bound mRNAs are stored in a silenced and deadenylated form

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2020
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Abstract
Human 4E-T is an eIF4E-binding protein (4E-BP) present in processing (P)-bodies that represses translation and regulates decay of mRNAs destabilized by AU-rich elements and microRNAs (miRNAs). However, the underlying regulatory mechanisms are still unclear. ...
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Authors Felix Räsch, Ramona Weber, Elisa Izaurralde, Cátia Igreja;Felix Räsch;Ramona Weber;Elisa Izaurralde;Cátia Igreja;
Journal genes & development
Year 2020
DOI
10.1101/gad.336073.119
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