WNT signaling in the control of hair growth and structure

Clicks: 282
ID: 273696
1999
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Abstract
Characterization of the molecular pathways controlling differentiation and proliferation in mammalian hair follicles is central to our understanding of the regulation of normal hair growth, the basis of hereditary hair loss diseases, and the origin of follicle-based tumors. We demonstrate that the p …
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Authors Millar SE;Willert K;Salinas PC;Roelink H;Nusse R;Sussman DJ;Barsh GS;;
Journal Developmental biology
Year 1999
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/10049570
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice RNA gel gene expression regulation animals pubmed abstract nih national institutes of health national library of medicine phenotype fluorescent antibody technique microscopy in situ hybridization messenger / metabolism electron electrophoresis proteins / genetics* transgenic cell differentiation / genetics histocytochemistry proto-oncogene proteins / genetics* adaptor proteins signal transducing wnt proteins wnt3 protein dishevelled proteins two-dimensional phosphoproteins hair / ultrastructure hair follicle / cytology hair / growth & development* pmid:10049570 doi:10.1006/dbio.1998.9140 s e millar k willert g s barsh epidermis / embryology developmental / genetics* hair / cytology hair follicle / growth & development signal transduction / genetics* transgenes / genetics

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