Immunochromatography in CSF improves data on surveillance of S. pneumoniae meningitis in India.

Clicks: 398
ID: 27359
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Star

Ranked #8 of 23 articles by views in journal of infection and public health

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Streptococcus pneumoniae is a significant cause of childhood bacterial meningitis in India. The United States Food and Drug Administration has licensed an immunochromatographic (ICT) test, BinaxNOW™, to detect the C polysaccharide antigen of S. pneumoniae in cerebrospinal fluids (CSF). Accurate etiological diagnosis of bacterial meningitis in India is essential for effective treatment strategies and preventive interventions.CSF samples from 2081 children admitted, with clinically suspected bacterial meningitis at 11 sentinel sites of hospital based sentinel surveillance network for bacterial meningitis in India between September 2009 and December 2016 were tested with ICT. Concurrent CSF cultures were processed using standard procedures.S. pneumoniae was detected thrice the number of times by ICT than by CSF culture, with a sensitivity and specificity of 100% and 95.3% respectively. This rapid ICT test proves to be of immense use as a diagnostic test for meningitis patients with/without prior antibiotic treatment, especially in facilities with limited laboratory infrastructure in resource limited settings.
Reference Key
jayaramanimmunochromatographyjournal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Jayaraman, Yuvaraj;Mehendale, Sanjay;Jayaraman, Ranjith;Varghese, Rosemol;Chethrapilly Purushothaman, Girish K;Rajkumar, Prabu;Sukumar, Bharathy;Pillai, Rajamohanan K;Mohan, Girija;Radhakrishnan, Devasena N;Sridharan, Sujatha;Babu, Narayan;Ganesapillai, Mathevan;Rao, Sugandhi P;Kar, Shantanu K;Manchanda, Vikas;Kanga, Anil;Verghese, Valsan P;Veeraraghavan, Balaji;
Journal journal of infection and public health
Year Year not found
DOI
S1876-0341(18)30003-0
URL
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.