Enteric infections, diarrhea, and their impact on function and development

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ID: 273560
2008
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Abstract
Enteric infections, with or without overt diarrhea, have profound effects on intestinal absorption, nutrition, and childhood development as well as on global mortality. Oral rehydration therapy has reduced the number of deaths from dehydration caused by infection with an enteric pathogen, but it has not changed the morbidity caused by such infections. This Review focuses on the interactions between enteric pathogens and human genetic determinants that alter intestinal function and inflammation and profoundly impair human health and development. We also discuss specific implications for novel approaches to interventions that are now opened by our rapidly growing molecular understanding.
Reference Key
guerrant2008journalenteric Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors William A. Petri,Mark Miller,Henry J. Binder,Myron M. Levine,Rebecca Dillingham,Richard L. Guerrant;William A. Petri;Mark Miller;Henry J. Binder;Myron M. Levine;Rebecca Dillingham;Richard L. Guerrant;
Journal Journal of Clinical Investigation
Year 2008
DOI
10.1172/jci34005
URL
https://sciprofiles.com/publication/view/4d43efd72d32d7479599650e470e0e23
Keywords
diarrhea pathogens function absorption dehydration rapidly rehydration overt profoundly

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