Bronchodilating Action of Vasicinone and Related Compounds - Nature

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ID: 273557
1970
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Abstract
Amin and Mehta have claimed1 that vasicinone (I), which they obtained by aerial oxidation in sunlight of crude extracts of Adhatoda vasica or of pure vasicine (II), the shrub's main alkaloid, has a bronchodilating action. They suggested that this property is attributable to the quinazol-4-one ring system for they found it to be common to the parent substance (III) and various simple derivatives2. Vasicine, on the other hand, proved to have a bronchoconstricting action, and the bronchodilator effects variously attributed3 to preparations containing it they ascribed to contamination by small amounts of vasicinone.
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w.1970naturebronchodilating Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors CAMBRIDGE, G. W.;JANSEN, A. B. A.;JARMAN, D. A.;CAMBRIDGE, G. W.;JANSEN, A. B. A.;JARMAN, D. A.;
Journal Nature
Year 1970
DOI
doi:10.1038/1961217a0
URL
https://doi.org/10.1038/1961217a0
Keywords
Science humanities and social sciences multidisciplinary

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