SIX4 promotes hepatocellular carcinoma metastasis through upregulating YAP1 and c-MET

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ID: 273466
2020
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Abstract
Metastasis is the main reason for high mortality in hepatocellular carcinoma (HCC) patients and the molecular mechanism remains unclear. Therefore, it is important to elucidate the mechanism underlying HCC metastasis. Here, we report a novel role of SIX homeobox 4 (SIX4), one of the SIX gene family, …
Reference Key
q2020oncogenesix4 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors He Q;Lin Z;Wang Z;Huang W;Tian D;Liu M;Xia L;;
Journal Oncogene
Year 2020
DOI
DOI not found
URL
https://www.pubmed.gov/33046796/
Keywords
Tumor National Center for Biotechnology Information NCBI NLM MEDLINE genetic Mice animals humans pubmed abstract nih national institutes of health national library of medicine prognosis research support non-u.s. gov't female male middle aged cell line Transcription Factors / metabolism* transcription carcinoma signal transduction cell transformation neoplastic neoplasm metastasis up-regulation liver neoplasms / genetics liver neoplasms / diagnosis trans-activators / metabolism* adaptor proteins hepatocellular / metabolism* liver neoplasms / metabolism* hepatocellular / pathology* signal transducing / metabolism* homeodomain proteins / metabolism* pmid:33046796 doi:10.1038/s41388-020-01500-y qin he zhuoying lin limin xia hepatocellular / diagnosis hepatocellular / genetics liver neoplasms / pathology* proto-oncogene proteins c-met / metabolism*

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