A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans

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ID: 273461
2002
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Abstract
Messenger RNA regulation is a critical mode of controlling gene expression. Regulation of mRNA stability and translation is linked to controls of poly(A) tail length. Poly(A) lengthening can stabilize and translationally activate mRNAs, whereas poly(A) removal can trigger degradation and translation …
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Authors Wang L;Eckmann CR;Kadyk LC;Wickens M;Kimble J;;
Journal Nature
Year 2002
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/12239571
Keywords
Evolution National Center for Biotechnology Information NCBI NLM MEDLINE Molecular RNA animals pubmed abstract nih national institutes of health national library of medicine models research support non-u.s. gov't u.s. gov't amino acid sequence P.H.S. Molecular Sequence Data Messenger / genetics messenger / metabolism biological embryo cloning protein binding protein structure tertiary caenorhabditis elegans / genetics poly a / metabolism catalytic domain liaoteng wang polynucleotide adenylyltransferase / chemistry polynucleotide adenylyltransferase / genetics* polynucleotide adenylyltransferase / metabolism* dimerization rna-binding proteins / genetics rna-binding proteins / metabolism polyadenylation pmid:12239571 doi:10.1038/nature01039 christian r eckmann judith kimble caenorhabditis elegans / embryology caenorhabditis elegans / enzymology* caenorhabditis elegans proteins / chemistry caenorhabditis elegans proteins / genetics* caenorhabditis elegans proteins / immunology caenorhabditis elegans proteins / metabolism* cytoplasm / enzymology* nonmammalian / enzymology germ-line mutation / genetics polynucleotide adenylyltransferase / immunology helminth / genetics helminth / metabolism rna-binding proteins / chemistry rna-binding proteins / immunology

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