Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms

Clicks: 304
ID: 273424
1998
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Abstract
Traditional and molecular typing schemes for the characterization of pathogenic microorganisms are poorly portable because they index variation that is difficult to compare among laboratories. To overcome these problems, we propose multilocus sequence typing (MLST), which exploits the unambiguous na …
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Authors Maiden MC;Bygraves JA;Feil E;Morelli G;Russell JE;Urwin R;Zhang Q;Zhou J;Zurth K;Caugant DA;Feavers IM;Achtman M;Spratt BG;;
Journal Proceedings of the National Academy of Sciences of the United States of America
Year 1998
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/9501229
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't Comparative Study Bacterial Genes Sequence Analysis Molecular Sequence Data DNA / methods* evaluation studies as topic bacterial typing techniques* neisseria meningitidis / pathogenicity cluster analysis virulence / genetics gene frequency pmid:9501229 pmc19708 doi:10.1073/pnas.95.6.3140 m c maiden j a bygraves b g spratt meningococcal infections / microbiology* neisseria meningitidis / classification* neisseria meningitidis / genetics*

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