Genetic regressive trajectories in colorectal cancer: A new hallmark of oligo-metastatic disease?

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2021
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Abstract
Colorectal cancer (CRC) originates as consequence of multiple genetic alterations. Some of the involved genes have been extensively studied (APC, TP53, KRAS, SMAD4, PIK3CA, MMR genes) in highly heterogeneous and poly-metastatic cohorts. However, about 10% of metastatic CRC patients presents with an …
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Authors Ottaiano A;Santorsola M;Caraglia M;Circelli L;Gigantino V;Botti G;Nasti G;;
Journal translational oncology
Year 2021
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