IL-10 mediates susceptibility to Leishmania donovani infection

Clicks: 215
ID: 273307
2001
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Abstract
Human visceral leishmaniasis (VL) results in a severe and potentially fatal systemic disease, accompanied by cellular immune depression. The production of IL-10 correlates with ongoing disease and it has been suggested that the cellular immune depression that accompanies active disease may be due to …
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Authors Murphy ML;Wille U;Villegas EN;Hunter CA;Farrell JP;;
Journal european journal of immunology
Year 2001
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/11592059
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice Inbred C57BL animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't female P.H.S. Inbred BALB C interferon-gamma / biosynthesis nitric oxide / biosynthesis leishmaniasis visceral / immunology* nitric oxide synthase type ii pmid:11592059 doi:10.1002/1521-4141(2001010)31:10<2848::aid-immu2848>3.0.co;2-t m l murphy u wille j p farrell granuloma / enzymology interleukin-10 / physiology* interleukin-12 / physiology leishmania donovani* liver diseases / enzymology nitric oxide synthase / biosynthesis

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