Clinical and neurophysiological study of the effects of multiple doses of artemisinin on brain-stem function in Vietnamese patients

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ID: 273290
1970
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Abstract
The qinghaosu (artemisinin) group of drugs is the most important new class of antimalarials developed in the last fifty years. Although there has been no clinical evidence of neurotoxicity, an unusual pattern of damage to specific brain-stem nuclei has been reported in experimental animals receiving …
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Authors Kissinger E;Hien TT;Hung NT;Nam ND;Tuyen NL;Dinh BV;Mann C;Phu NH;Loc PP;Simpson JA;White NJ;Farrar JJ;;
Journal The American journal of tropical medicine and hygiene
Year 1970
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/11357994
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't adult female male adolescent aged middle aged Child Infant Drug Administration Schedule preschool case-control studies mefloquine / administration & dosage antimalarials / therapeutic use malaria / drug therapy malaria / epidemiology antimalarials / administration & dosage vietnam / epidemiology neurologic examination evoked potentials artemisinins* auditory brain stem / drug effects* mefloquine / therapeutic use sesquiterpenes / therapeutic use t t hien pmid:11357994 doi:10.4269/ajtmh.2000.63.48 e kissinger j j farrar antimalarials / pharmacology* mefloquine / pharmacology* sesquiterpenes / administration & dosage sesquiterpenes / pharmacology*

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