Regulation of the mevalonate pathway
Clicks: 221
ID: 273196
1990
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Abstract
The mevalonate pathway produces isoprenoids that are vital for diverse cellular functions, ranging from cholesterol synthesis to growth control. Several mechanisms for feedback regulation of low-density-lipoprotein receptors and of two enzymes involved in mevalonate biosynthesis ensure the productio …
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| Authors | Goldstein JL;Brown MS;; |
| Journal | Nature |
| Year | 1990 |
| DOI |
DOI not found
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| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
P.H.S.
Receptors
gene expression regulation / drug effects
genetic / drug effects
transcription
cell division
j l goldstein
m s brown
LDL / genetics
pmid:1967820
doi:10.1038/343425a0
cholesterol / biosynthesis
farnesol / metabolism
hydroxymethylglutaryl coa reductases / genetics
hydroxymethylglutaryl-coa synthase / genetics
mevalonic acid / metabolism*
sterols / pharmacology
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