Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

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ID: 273168
2007
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Abstract
Polycomb-repressive complex 2 (PRC2)-mediated histone methylation plays an important role in aberrant cancer gene silencing and is a potential target for cancer therapy. Here we show that S-adenosylhomocysteine hydrolase inhibitor 3-Deazaneplanocin A ...
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yu2007genespharmacologic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Jing Tan, Xiaojing Yang, Li Zhuang, Xia Jiang, Wei Chen, Puay Leng Lee, R.K. Murthy Karuturi, Patrick Boon Ooi Tan, Edison T. Liu, Qiang Yu;Jing Tan;Xiaojing Yang;Li Zhuang;Xia Jiang;Wei Chen;Puay Leng Lee;R.K. Murthy Karuturi;Patrick Boon Ooi Tan;Edison T. Liu;Qiang Yu;
Journal genes & development
Year 2007
DOI
10.1101/gad.1524107
URL
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855231/
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