Cooperation by sterol regulatory element-binding protein and Sp1 in sterol regulation of low density lipoprotein receptor gene

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ID: 273096
1995
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Abstract
Regulation of the low density lipoprotein (LDL) receptor promoter by cholesterol requires a well defined sterol regulatory site and an adjacent binding site for the universal transcription factor Sp1. These elements are located in repeats 2 and 3 of the wild type promoter, respectively. The experime …
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Authors Sanchez HB;Yieh L;Osborne TF;;
Journal The Journal of biological chemistry
Year 1995
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/7836375
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE genetic Drosophila animals humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't cell line DNA DNA-Binding Proteins / metabolism* Nuclear Proteins / metabolism* Receptors Base Sequence Molecular Sequence Data Gene Expression Regulation* Promoter Regions transcription factors* sterol regulatory element binding protein 1 ldl / genetics* ccaat-enhancer-binding proteins* sp1 transcription factor / metabolism* h b sanchez t f osborne sterols / metabolism* pmid:7836375 doi:10.1074/jbc.270.3.1161 l yieh

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