Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro

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ID: 272947
1995
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Abstract
The CBP protein mediates PKA induced transcription by binding to the PKA phosphorylated activation domain of CREB. Here we show that CBP also stimulates the activity of both c-Jun and v-Jun in vivo. The CREB binding domain of CBP is sufficient to contact to c-Jun in vitro. When this domain of CBP is …
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Authors Bannister AJ;Oehler T;Wilhelm D;Angel P;Kouzarides T;;
Journal Oncogene
Year 1995
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/8545107
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't transcription factors / metabolism phosphorylation transcriptional activation binding sites a j bannister t kouzarides transcription factors / pharmacology* pmid:8545107 t oehler proto-oncogene proteins c-jun / metabolism*

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