Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro
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ID: 272947
1995
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Abstract
The CBP protein mediates PKA induced transcription by binding to the PKA phosphorylated activation domain of CREB. Here we show that CBP also stimulates the activity of both c-Jun and v-Jun in vivo. The CREB binding domain of CBP is sufficient to contact to c-Jun in vitro. When this domain of CBP is …
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| Reference Key |
aj1995oncogenestimulation
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|---|---|
| Authors | Bannister AJ;Oehler T;Wilhelm D;Angel P;Kouzarides T;; |
| Journal | Oncogene |
| Year | 1995 |
| DOI |
DOI not found
|
| URL | |
| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
transcription factors / metabolism
phosphorylation
transcriptional activation
binding sites
a j bannister
t kouzarides
transcription factors / pharmacology*
pmid:8545107
t oehler
proto-oncogene proteins c-jun / metabolism*
|
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