Formation of regulator/target gene relationships during evolution

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2000
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Abstract
The Foxn1-like forkhead/winged-helix transcription factor genes have been maintained in single copy throughout chordate evolution. Among other functions, Foxn1 (formerly known as Whn) regulates the expression of hair keratin genes in the hair follicle, which represents an evolutionarily novel organ …
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Authors Schlake T;Schorpp M;Boehm T;;
Journal Gene
Year 2000
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/11054532
Keywords
Evolution National Center for Biotechnology Information NCBI NLM MEDLINE gene expression gene expression regulation animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't amino acid sequence sequence alignment DNA Molecular* Genes Sequence Analysis Molecular Sequence Data complementary / genetics sequence homology amino acid dna-binding proteins / physiology dna-binding proteins / genetics transcription factors / genetics transcriptional activation drosophila melanogaster / genetics transcription factors / physiology zebrafish / genetics complementary / chemistry dna / genetics forkhead transcription factors pmid:11054532 doi:10.1016/s0378-1119(00)00344-9 t schlake m schorpp t boehm chordata nonvertebrate / genetics dna / chemistry regulator / genetics* regulator / physiology

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