PhaseÂ I/II study of COVID-19 RNA vaccine BNT162b1 in adults - Nature

Mulligan, Mark J.; Lyke, Kirsten E.; Kitchin, Nicholas; Absalon, Judith; Gurtman, Alejandra; Lockhart, Stephen; Neuzil, Kathleen; Raabe, Vanessa; Bailey, Ruth; Swanson, Kena A.; Li, Ping; Koury, Kenneth; Kalina, Warren; Cooper, David; Fontes-Garfias, Camila; Shi, Pei-Yong; Türeci, Özlem; Tompkins, Kristin R.; Walsh, Edward E.; Frenck, Robert; Falsey, Ann R.; Dormitzer, Philip R.; Gruber, William C.; Şahin, Uğur; Jansen, Kathrin U.

doi:10.1038/s41586-020-2639-4

PhaseÂ I/II study of COVID-19 RNA vaccine BNT162b1 in adults - Nature

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ID: 272847

2020

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Abstract

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In a dose-escalation study of the COVID-19 RNA vaccine BNT162b1 in 45 healthy adults, RBD-binding IgG concentrations and SARS-CoV-2 neutralizing titres in sera increased with dose level and after a second vaccine dose.

Reference Key	j.2020naturephaseÂ i/ii Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors	Mark J. Mulligan, Kirsten E. Lyke, Nicholas Kitchin, Judith Absalon, Alejandra Gurtman, Stephen Lockhart, Kathleen Neuzil, Vanessa Raabe, Ruth Bailey, Kena A. Swanson, Ping Li, Kenneth Koury, Warren Kalina, David Cooper, Camila Fontes-Garfias, Pei-Yong Shi, Özlem Türeci, Kristin R. Tompkins, Edward E. Walsh, Robert Frenck, Ann R. Falsey, Philip R. Dormitzer, William C. Gruber, Uğur Şahin, Kathrin U. Jansen Are you one of these authors? Claim your profile
Journal	Nature
Year	2020
DOI	doi:10.1038/s41586-020-2639-4 Searching for DOI...
URL	https://www.nature.com/articles/s41586-020-2639-4 https://doi.org/doi:10.1038/s41586-020-2639-4
Keywords	viral infection randomized controlled trials drug development sars-cov-2

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