TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease

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ID: 272846
2021
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Abstract
Obesity is characterized by the excessive accumulation of the white adipose tissue (WAT), but healthy expansion of WAT via adipocyte hyperplasia can offset the negative metabolic effects of obesity. Thus, identification of novel adipogenesis regulators that promote hyperplasia may lead to effective …
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Authors Zhao GN;Tian ZW;Tian T;Zhu ZP;Zhao WJ;Tian H;Cheng X;Hu FJ;Hu ML;Tian S;Ding T;Chen S;Ji YX;Zhang P;Zhang XJ;She ZG;Yuan Y;Chen W;Bai L;Li H;;
Journal cell metabolism
Year 2021
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