Empty Sella Syndrome Secondary to Intrasellar Cyst in Adolescence

Clicks: 354
ID: 272780
1976
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Abstract
A 15-year-old boy had growth failure and failure of sexual development. The probable onset was at age 10. Endocrine studies showed hypopituitarism with deficiency of growth hormone and follicle-stimulating hormone, an abnormal response to metyrapone, and deficiency of thyroid function. Luteinizing hormone level was in the low-normal range. Posterior pituitary function was normal. Roentgenogram showed a large sella with some destruction of the posterior clinoids. Transsphenoidal exploration was carried out. The sella was empty except for a whitish membrane; no pituitary tissue was seen. The sella was packed with muscle. Recovery was uneventful, and the patient was given replacement therapy. On histologic examination,the cyst wall showed low pseudostratified cuboidal epithelium and occasional squamous metaplasia. Hemosiderin-filled phagocytes and acinar structures were also seen. The diagnosis was probable rupture of an intrasellar epithelial cyst, leading to empty sella syndrome.
Reference Key
raiti1976archivesempty Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Salvatore Raiti;Salvatore Raiti;
Journal archives of pediatrics & adolescent medicine
Year 1976
DOI
10.1001/archpedi.1976.02120100099017
URL
https://sciprofiles.com/publication/view/e077bd854a976593892398c34c03e839
Keywords
pituitary cyst deficiency function structures hormone posterior empty intrasellar

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