Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling

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2001
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Abstract
G protein-coupled receptors (GPCRs) are seven transmembrane proteins that form the largest single family of integral membrane receptors. GPCRs transduce information provided by extracellular stimuli into intracellular second messengers via their coupling to heterotrimeric G proteins and the subseque …
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Authors Ferguson SS;;
Journal pharmacological reviews
Year 2001
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