Complex protein interactions within the human polyadenylation machinery identify a novel component

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2000
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Abstract
Polyadenylation of mRNA precursors is a two-step reaction requiring multiple protein factors. Cleavage stimulation factor (CstF) is a heterotrimer necessary for the first step, endonucleolytic cleavage, and it plays an important role in determining the efficiency of polyadenylation. Although a consi …
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Journal molecular and cellular biology
Year 2000
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