Ancient human genome sequence of an extinct Palaeo-Eskimo

已灭绝古爱斯基摩人的古人类基因组序列

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ID: 272703
2010
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Abstract
We report here the genome sequence of an ancient human. Obtained from approximately 4,000-year-old permafrost-preserved hair, the genome represents a male individual from the first known culture to settle in Greenland. Sequenced to an average depth of 20x, we recover 79% of the diploid genome, an am …
本文报道了一例古人类的基因组序列。该基因组提取自保存于多年冻土中、距今约4,000年的毛发，代表了已知最早定居格陵兰岛的文化中的一名男性个体。在20×的平均测序深度下，我们恢复了该二倍体基因组的79%，这一……
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Authors Rasmussen M, Li Y, Lindgreen S, Pedersen JS, Albrechtsen A, Moltke I, Metspalu M, Metspalu E, Kivisild T, Gupta R, Bertalan M, Nielsen K, Gilbert MT, Wang Y, Raghavan M, Campos PF, Kamp HM, Wilson AS, Gledhill A, Tridico S, Bunce M, Lorenzen ED, Binladen J, Guo X, Zhao J, Zhang X, Zhang H, Li Z, Chen M, Orlando L, Kristiansen K, Bak M, Tommerup N, Bendixen C, Pierre TL, Grønnow B, Meldgaard M, Andreasen C, Fedorova SA, Osipova LP, Higham TF, Ramsey CB, Hansen TV, Nielsen FC, Crawford MH, Brunak S, Sicheritz-Pontén T, Villems R, Nielsen R, Krogh A, Wang J, Willerslev E
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Journal Nature
Year 2010
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/20148029
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Genetics humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't non-p.h.s. male DNA Sequence Analysis genome phenotype human / genetics* Phylogeny Genotype Polymorphism biological* historical article history genomics population ancient cryopreservation* single nucleotide / genetics pmid:20148029 pmc3951495 doi:10.1038/nature08835 morten rasmussen yingrui li eske willerslev emigration and immigration / history extinction greenland hair inuits / genetics* siberia / ethnology

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