RINGO/cdk1 and CPEB mediate poly(A) tail stabilization and translational regulation by ePAB

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ID: 272602
2007
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Abstract
One activity that controls mRNA translation in vertebrate oocytes, embryos, and neurons is cytoplasmic polyadenylation. In Xenopus oocytes, where much of the biochemistry of this process has been elucidated, nuclear pre-mRNAs containing a cytoplasmic polyadenylation element (CPE) in their 3' untrans …
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Autoren Kim JH;Richter JD;;
Zeitschrift genes & development
Jahr 2007
DOI
DOI nicht gefunden
URL
http://www.ncbi.nlm.nih.gov/pubmed/17938241
Schlüsselwörter
National Center for Biotechnology Information NCBI NLM MEDLINE RNA animals pubmed abstract nih national institutes of health national library of medicine models research support female N.I.H. Extramural protein biosynthesis Transcription Factors / metabolism* Messenger / genetics in vitro techniques biological transcription factors / genetics cell cycle proteins / genetics cell cycle proteins / metabolism* mutagenesis amino acid substitution messenger / metabolism* transcription factors / chemistry site-directed xenopus proteins / genetics cdc2 protein kinase / metabolism* xenopus laevis joel d richter oocytes / metabolism xenopus proteins / metabolism* rna stability jong heon kim pmid:17938241 pmc2000322 doi:10.1101/gad.1593007 cdc2 protein kinase / genetics eukaryotic initiation factor-4g / genetics eukaryotic initiation factor-4g / metabolism poly(a)-binding proteins / genetics poly(a)-binding proteins / metabolism* xenopus proteins / chemistry mrna cleavage and polyadenylation factors / chemistry mrna cleavage and polyadenylation factors / genetics mrna cleavage and polyadenylation factors / metabolism*

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