Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

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ID: 272493
2005
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Abstract
Type 1 and type 2 diabetes are characterized by progressive beta-cell failure. Apoptosis is probably the main form of beta-cell death in both forms of the disease. It has been suggested that the mechanisms leading to nutrient- and cytokine-induced beta-cell death in type 2 and type 1 diabetes, respe …
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Authors Cnop M;Welsh N;Jonas JC;Jörns A;Lenzen S;Eizirik DL;;
Journal Diabetes
Year 2005
DOI
DOI not found
URL
https://www.ncbi.nlm.nih.gov/pubmed/16306347
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE review humans pubmed abstract nih national institutes of health national library of medicine models research support non-u.s. gov't N.I.H. Extramural Comparative Study biological diabetes mellitus type 2 / immunology type 2 / pathology* insulin-secreting cells / pathology* interferon-gamma / physiology pmid:16306347 doi:10.2337/diabetes.54.suppl_2.s97 miriam cnop nils welsh decio l eizirik cell death* type 1 / immunology type 1 / pathology* interleukin-1 / physiology

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