Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle

Clicks: 208
ID: 272041
2006
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Abstract
AMP-activated protein kinase (AMPK) is a key regulator of cellular energy balance and of the effects of leptin on food intake and fatty acid oxidation. Obesity is usually associated with resistance to the effects of leptin on food intake and body weight. To determine whether diet-induced obesity (DI …
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Authors Martin TL;Alquier T;Asakura K;Furukawa N;Preitner F;Kahn BB;;
Journal The Journal of biological chemistry
Year 2006
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/16687413
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't male N.I.H. Extramural Body Weight energy metabolism leptin / metabolism fatty acids / metabolism muscle Acetyl-CoA Carboxylase / metabolism oxygen / metabolism amp-activated protein kinases protein-serine-threonine kinases / physiology* pmid:16687413 doi:10.1074/jbc.m512831200 tonya l martin thierry alquier barbara b kahn animal feed* hypothalamus / enzymology* hypothalamus / pathology multienzyme complexes / physiology* skeletal / enzymology* obesity*

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