Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer’s disease
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ID: 272015
2021
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Abstract
Microglia-mediated neuroinflammation has been implicated in the pathogenesis of Alzheimer’s disease (AD). Although microglia in aging and neurodegenerative disease model mice show a loss of homeostatic phenotype and activation of disease-associated ...
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| Reference Key |
yamanaka2021actamicroglial
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| Authors | Akira Sobue, Okiru Komine, Yuichiro Hara, Fumito Endo, Hiroyuki Mizoguchi, Seiji Watanabe, Shigeo Murayama, Takashi Saito, Takaomi C. Saido, Naruhiko Sahara, Makoto Higuchi, Tomoo Ogi, Koji Yamanaka;Akira Sobue;Okiru Komine;Yuichiro Hara;Fumito Endo;Hiroyuki Mizoguchi;Seiji Watanabe;Shigeo Murayama;Takashi Saito;Takaomi C. Saido;Naruhiko Sahara;Makoto Higuchi;Tomoo Ogi;Koji Yamanaka; |
| Journal | acta neuropathologica communications |
| Year | 2021 |
| DOI |
10.1186/s40478-020-01099-x
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