Gene Ontology: tool for the unification of biology - Nature Genetics

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ID: 271958
1970
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Abstract
Genomic sequencing has made it clear that a large fraction of the genes specifying the core biological functions are shared by all eukaryotes. Knowledge of the biological role of such shared proteins in one organism can often be transferred to other organisms. The goal of the Gene Ontology Consortium is to produce a dynamic, controlled vocabulary that can be applied to all eukaryotes even as knowledge of gene and protein roles in cells is accumulating and changing. To this end, three independent ontologies accessible on the World-Wide Web ( http://www.geneontology.org ) are being constructed: biological process, molecular function and cellular component.
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Authors Ashburner, Michael;Ball, Catherine A.;Blake, Judith A.;Botstein, David;Butler, Heather;Cherry, J. Michael;Davis, Allan P.;Dolinski, Kara;Dwight, Selina S.;Eppig, Janan T.;Harris, Midori A.;Hill, David P.;Issel-Tarver, Laurie;Kasarskis, Andrew;Lewis, Suzanna;Matese, John C.;Richardson, Joel E.;Ringwald, Martin;Rubin, Gerald M.;Sherlock, Gavin;Ashburner, Michael;Ball, Catherine A.;Blake, Judith A.;Botstein, David;Butler, Heather;Cherry, J. Michael;Davis, Allan P.;Dolinski, Kara;Dwight, Selina S.;Eppig, Janan T.;Harris, Midori A.;Hill, David P.;Issel-Tarver, Laurie;Kasarskis, Andrew;Lewis, Suzanna;Matese, John C.;Richardson, Joel E.;Ringwald, Martin;Rubin, Gerald M.;Sherlock, Gavin;
Journal nature genetics
Year 1970
DOI
doi:10.1038/75556
URL
https://www.nature.com/articles/ng0500_25
Keywords
agriculture biomedicine cancer research general animal genetics and genomics human genetics gene function

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