Function and biological roles of the Dickkopf family of Wnt modulators

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ID: 271927
2006
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Abstract
Dickkopf (Dkk) genes comprise an evolutionary conserved small gene family of four members (Dkk1-4) and a unique Dkk3-related gene, Dkkl1 (soggy). They encode secreted proteins that typically antagonize Wnt/beta-catenin signaling, by inhibiting the Wnt coreceptors Lrp5 and 6. Additionally, Dkks are h …
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c2006oncogenefunction Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Niehrs C;;
Journal Oncogene
Year 2006
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17143291
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice review animals humans pubmed abstract nih national institutes of health national library of medicine models research support non-u.s. gov't conserved sequence neoplasms / metabolism biological signal transduction wnt proteins / physiology* cell lineage xenopus xenopus proteins / physiology* wnt proteins / metabolism pmid:17143291 doi:10.1038/sj.onc.1210054 c niehrs body patterning intercellular signaling peptides and proteins / physiology* ldl-receptor related proteins / metabolism low density lipoprotein receptor-related protein-6

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