Modulation of cellular apoptotic potential: contributions to oncogenesis

Clicks: 229
ID: 271700
1999
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Abstract
The importance of apoptosis as a natural means to eliminate unwanted or damaged cells has been realized over the past decade. Many components required to exercise programmed cell death have been identified and shown to pre-exist in most, if not all, cells. Such ubiquity requires that apoptosis be ti …
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Authors Stambolic V;Mak TW;Woodgett JR;;
Journal Oncogene
Year 1999
DOI
DOI not found
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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10557100
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE review animals humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't drosophila melanogaster / physiology phosphoinositide-3 kinase inhibitors neoplasms / therapy caenorhabditis elegans / genetics drosophila melanogaster / genetics signal transduction* / genetics neoplasms / pathology* apoptosis / physiology* phosphatidylinositol 3-kinases / metabolism pten phosphohydrolase proto-oncogene proteins c-akt proto-oncogene proteins / metabolism* drosophila proteins protein-serine-threonine kinases* phosphoric monoester hydrolases / metabolism neoplasms / enzymology* pmid:10557100 doi:10.1038/sj.onc.1203126 v stambolic t w mak j r woodgett caenorhabditis elegans / enzymology caenorhabditis elegans / physiology cell survival / physiology drosophila melanogaster / enzymology phosphatidylinositol 3-kinases / genetics tumor suppressor proteins*

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