Botulinum neurotoxins: genetic, structural and mechanistic insights - Nature Reviews Microbiology

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ID: 271640
2014
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Abstract
Botulinum neurotoxins, which are the most powerful known toxins, are produced by toxigenic clostridia and cause persistent paralysis of peripheral nerve terminals by blocking neurotransmitter release. In this Review, Montecucco and colleagues discuss recent structural and molecular insights into the mechanisms of toxin entry into nerve terminals, membrane translocation and neuroparalysis.
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ornella2014naturebotulinum Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Rossetto, Ornella;Pirazzini, Marco;Montecucco, Cesare;Rossetto, Ornella;Pirazzini, Marco;Montecucco, Cesare;
Journal Nature Reviews Microbiology
Year 2014
DOI
doi:10.1038/nrmicro3295
URL
http://dx.doi.org/10.1038/nrmicro3295
Keywords
bacterial pathogenesis bacterial structural biology bacterial toxins

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