Genetic, biochemical, and clinical features of chronic granulomatous disease

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2000
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Abstract
The reduced nicotinamide dinucleotide phosphate (NADPH) oxidase complex allows phagocytes to rapidly convert O2 to superoxide anion which then generates other antimicrobial reactive oxygen intermediates, such as H2O2, hydroxyl anion, and peroxynitrite anion. Chronic granulomatous disease (CGD) resul …
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bh2000medicinegenetic, Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Segal BH;Leto TL;Gallin JI;Malech HL;Holland SM;;
Journal Medicine
Year 2000
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/10844936
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice review animals humans pubmed abstract nih national institutes of health national library of medicine models female male Infections / complications mutation biological inflammation / etiology infections / microbiology infections / therapy inflammation / physiopathology heterozygote granulomatous disease nadph oxidases / metabolism chronic* / diagnosis chronic* / therapy pmid:10844936 doi:10.1097/00005792-200005000-00004 b h segal t l leto s m holland chronic* / genetics chronic* / immunology chronic* / microbiology chronic* / physiopathology nadph oxidases / chemistry nadph oxidases / genetics

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