Phospho-β-catenin expression in primary and metastatic melanomas and in tumor-free visceral tissues, and associations with expression of PD-L1 and PD-L2
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2021
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Abstract
β-catenin (βcat) is an important downstream effector in the Wnt signaling pathway and plays important roles in the development and progression of many cancers including melanoma. βcat expression is regulated by GSK-3β-mediated phosphorylation at positions 33, 37 and 41. In normal cells, phosphorylat …
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| Authors | Pinczewski J;Obeng RC;Slingluff CL;Engelhard VH;; |
| Journal | pathology, research and practice |
| Year | 2021 |
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