In vitro and in vivo sensitivity of a non-mouse-adapted influenza A (Beijing) virus infection to amantadine and ribavirin

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1970
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Abstract
A clinically isolated non-mouse-adapted influenza A/Beijing/32/92 virus was assayed for sensitivity to amantadine and ribavirin in vitro and in mice. When multiple concentrations of each drug were assayed for ability to inhibit the virus-induced cytopathic effect in MDCK cells, the 50% effective (vi …
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Authors Sidwell RW;Bailey KW;Wong MH;Huffman JH;;
Journal chemotherapy
Year 1970
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/8529436
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't female P.H.S. Inbred BALB C antiviral agents / therapeutic use* ribavirin / therapeutic use* influenza a virus / drug effects* oxygen / blood ribavirin / pharmacology orthomyxoviridae infections / drug therapy* amantadine / pharmacology amantadine / therapeutic use* pmid:8529436 doi:10.1159/000239382 r w sidwell k w bailey j h huffman

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