Evaluation of intravenous zanamivir against experimental influenza A (H5N1) virus infection in cynomolgus macaques

Clicks: 387
ID: 271357
2008
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #16 of 31 articles by views in Antiviral research

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
We investigated the prophylactic and therapeutic efficacy of an intravenous (IV) formulation of zanamivir in a macaque infection model for highly pathogenic influenza A (H5N1) virus. Antiviral efficacy was dose-dependent, with no reduction in viral load observed at 2 mg/kg, but a significant reducti …
Reference Key
kj2008antiviralevaluation Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Stittelaar KJ;Tisdale M;van Amerongen G;van Lavieren RF;Pistoor F;Simon J;Osterhaus AD;;
Journal Antiviral research
Year 2008
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/18647621
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals humans pubmed abstract nih national institutes of health national library of medicine male Disease Models Animal Comparative Study influenza human / drug therapy* human / prevention & control antiviral agents / administration & dosage* influenza a virus human / virology h5n1 subtype / physiology pmid:18647621 doi:10.1016/j.antiviral.2008.06.014 k j stittelaar m tisdale a d m e osterhaus h5n1 subtype / drug effects* macaca zanamivir / administration & dosage*

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.