Cold-Inducible RNA-Binding Protein Prevents an Excessive Heart Rate Response to Stress by Targeting Phosphodiesterase

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ID: 271225
2020
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Abstract
CIRP acts as an mRNA stabilizer of specific PDEs to control the cAMP concentration in SAN, maintaining the appropriate heart rate stress response.
Reference Key
d2020circulationcold-inducible Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Xie D;Geng L;Xiong K;Zhao T;Wang S;Xue J;Wang C;Wang G;Feng Z;Zhou H;Li Y;Li L;Liu Y;Xue Z;Yang J;Ma H;Liang D;Chen YH;;
Journal circulation research
Year 2020
DOI
DOI not found
URL
https://www.pubmed.gov/32212953/
Keywords
Stress National Center for Biotechnology Information NCBI NLM MEDLINE animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't male Cells Cultured Myocytes Cardiac / physiology Rats Sprague-Dawley physiological cyclic amp / metabolism heart rate* rna-binding proteins / metabolism* pmid:32212953 doi:10.1161/circresaha.119.316322 duanyang xie li geng yi-han chen adrenergic beta-agonists / pharmacology cold shock proteins and peptides / genetics cold shock proteins and peptides / metabolism* cyclic nucleotide phosphodiesterases type 4 / genetics type 4 / metabolism* isoproterenol / pharmacology cardiac / drug effects cardiac / metabolism* phosphodiesterase inhibitors / pharmacology rna stability rna-binding proteins / genetics rolipram / pharmacology sinoatrial node / cytology sinoatrial node / metabolism sinoatrial node / physiology

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