Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1

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ID: 271153
1999
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Ranked #5 of 292 articles by views in Proceedings of the National Academy of Sciences of the United States of America

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Abstract
Expression of the DMP1 transcription factor, a cyclin D-binding Myb-like protein, induces growth arrest in mouse embryo fibroblast strains but is devoid of antiproliferative activity in primary diploid fibroblasts that lack the ARF tumor suppressor gene. DMP1 binds to a single canonical recognition …
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Authors Inoue K;Roussel MF;Sherr CJ;;
Journal Proceedings of the National Academy of Sciences of the United States of America
Year 1999
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