A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae

Clicks: 271
ID: 271145
1997
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Abstract
The S. cerevisiae MCD1 (mitotic chromosome determinant) gene was identified in genetic screens for genes important for chromosome structure. MCD1 is essential for viability and homologs are found from yeast to humans. Analysis of the mcd1 mutant and cell cycle-dependent expression pattern of Mcd1p s …
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Authors Guacci V;Koshland D;Strunnikov A;;
Journal Cell
Year 1997
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/9335334
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE genetic RNA gene expression regulation pubmed abstract nih national institutes of health national library of medicine models research support non-u.s. gov't u.s. gov't P.H.S. Genes mutation sequence homology amino acid chromosomes messenger / analysis cell cycle proteins / genetics cell division fungal / genetics saccharomyces cerevisiae / genetics* chromosomal proteins fungal / physiology* cell cycle proteins / physiology* v guacci d koshland fungal / analysis fungal proteins / genetics fungal / physiology phosphoproteins saccharomyces cerevisiae proteins chromatids / physiology* pmid:9335334 pmc2670185 doi:10.1016/s0092-8674(01)80008-8 a strunnikov cell cycle proteins / analysis cell nucleus / chemistry non-histone* nuclear proteins recombinant fusion proteins

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