216. Rasterelektronenmikroskopische Untersuchungsbefunde an Fremdoberflächen extrakorporaler Kreislaufsysteme

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ID: 271120
1977
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Abstract
Nach tierexperimentellen Langzeitperfusionen (12–24h) wurden die Oberflächen der extracorporalen Kreisläufe rasterelektronenmikroskopisch untersucht. An Stellen verlangsamter und/oder turbulenter Strömung kam es bevorzugt zur Ablagerung von Fibrin-, Thromben- und Zelldetritus. Diese Ablagerungen wurden sowohl in Kreisläufen einer Standardausrüstung unter Vollheparinisierung als auch in Kreisläufen, bei denen zur VerbeBerung der Kompatibilität eine blutkontaktseitige Beschichtung mit silica-free-silicone-ruber" bestand, unter reduzierter Heparindosierung gefunden. After long-term perfusion in animals (12–24 h) the surfaces of the extracorporeal circuits were studied by scanning electron microscopy. Especially at points of slow and/or turbulent flow patterns, there were deposits of fibrin, blood clots, and cell fragments. The deposits were observed in circuits of standard equipment and full heparinization as well as in circuits with a “silica-free silicone rubber”-coating for better compatibility and reduced heparinization.
Reference Key
schulte1977langenbecks216. Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors J. A. Herzer,K. Falke,K. A. Rosenbauer,H.-D. Schulte;J. A. Herzer;K. Falke;K. A. Rosenbauer;H.-D. Schulte;
Journal Langenbecks Archiv für Chirurgie
Year 1977
DOI
10.1007/bf01305662
URL
https://sciprofiles.com/publication/view/423d4cb710a1200ba7ec5abec52cf78b
Keywords
anticoagulants surface coating ekz beschichtung anticogulantien extracorporeal circuits

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