Sulforaphane enhances the activity of the Nrf2–ARE pathway and attenuates inflammation in OxyHb-induced rat vascular smooth muscle cells

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2013
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Abstract
A growing body of evidence indicates that the nuclear factor erythroid 2-related factor 2–antioxidant response element (Nrf2–ARE) pathway plays a protective role in many physiological stress processes such as inflammatory damage, oxidative stress, and the accumulation of toxic metabolites, which are all involved in the cerebral vasospasm following subarachnoid hemorrhage (SAH). We hypothesized that the Nrf2–ARE pathway might have a protective role in cerebral vasospasm following SAH.
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Authors X.-D. Zhao,Y.-T. Zhou,X.-J. Lu;X.-D. Zhao;Y.-T. Zhou;X.-J. Lu;
Journal inflammation research
Year 2013
DOI
10.1007/s00011-013-0641-0
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