Central effect of ghrelin, an endogenous growth hormone secretagogue, on hypothalamic peptide gene expression
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Abstract
Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor (GHS-R), was originally purified from the rat stomach. Like the synthetic GHSs, ghrelin specifically releases GH following intravenous administration. Also consistent with the central actions of GHSs, ghrelin-immunoreactive c …
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