The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer

Clicks: 349
ID: 271002
2005
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Star

Ranked #12 of 239 articles by views in Oncogene

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 239 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Wnt glycoproteins regulate homeostasis and development by binding to membrane Frizzled-LRP5/6 receptor complexes. Wnt signaling includes a canonical pathway involving cytosolic beta-catenin stabilization, nuclear translocation and gene regulation, acting as a co-activator of T-cell factor (TCF) prot …
Reference Key
jm2005oncogenethe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors González-Sancho JM;Aguilera O;García JM;Pendás-Franco N;Peña C;Cal S;García de Herreros A;Bonilla F;Muñoz A;;
Journal Oncogene
Year 2005
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=15592505
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE gene expression regulation humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't Genes neoplastic* proteins / genetics* gene expression profiling* signal transduction homeostasis down-regulation transcription factor 7-like 2 protein Tumor Suppressor wnt proteins beta catenin helix-loop-helix motifs tcf transcription factors pmid:15592505 doi:10.1038/sj.onc.1208303 josé manuel gonzález-sancho oscar aguilera alberto muñoz colonic neoplasms / genetics* colonic neoplasms / pathology* cytoskeletal proteins / pharmacology* dna-binding proteins / pharmacology* intercellular signaling peptides and proteins / pharmacology trans-activators / pharmacology* transcription factors / pharmacology* wnt1 protein

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.