Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita
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ID: 270718
2011
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Abstract
Dyskeratosis congenita (DC) is a genetic disorder of defective tissue maintenance and cancer predisposition caused by short telomeres and impaired stem cell function. Telomerase mutations are thought to precipitate DC by reducing either the catalytic ...
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| Reference Key |
artandi2011genesdisruption
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|---|---|
| Authors | Franklin Zhong, Sharon A. Savage, Marina Shkreli, Neelam Giri, Lea Jessop, Timothy Myers, Renee Chen, Blanche P. Alter, Steven E. Artandi;Franklin Zhong;Sharon A. Savage;Marina Shkreli;Neelam Giri;Lea Jessop;Timothy Myers;Renee Chen;Blanche P. Alter;Steven E. Artandi; |
| Journal | genes & development |
| Year | 2011 |
| DOI |
10.1101/gad.2006411
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| URL | |
| Keywords |
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