The RSC chromatin-remodeling complex influences mitotic exit and adaptation to the spindle assembly checkpoint by controlling the Cdc14 phosphatase

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2010
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Abstract
Upon prolonged activation of the spindle assembly checkpoint, cells escape from mitosis through a mechanism called adaptation or mitotic slippage, which is thought to underlie the resistance of cancer cells to antimitotic drugs. We show that, in budding yeast, this mechanism depends on known essenti …
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Authors Rossio V;Galati E;Ferrari M;Pellicioli A;Sutani T;Shirahige K;Lucchini G;Piatti S;;
Journal the journal of cell biology
Year 2010
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/21098112
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't Genes signal transduction cell cycle proteins / genetics cdc cell cycle proteins / metabolism saccharomyces cerevisiae / metabolism saccharomyces cerevisiae proteins / metabolism saccharomyces cerevisiae proteins / genetics saccharomyces cerevisiae / cytology pmid:21098112 pmc2995168 doi:10.1083/jcb.201007025 valentina rossio elena galati simonetta piatti chromatin assembly and disassembly* mitosis / physiology* phosphoprotein phosphatases / genetics phosphoprotein phosphatases / metabolism* protein tyrosine phosphatases / genetics protein tyrosine phosphatases / metabolism spindle apparatus / physiology*

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