A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat
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ID: 270489
2005
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Abstract
HIV-1 Tat binds human CyclinT1 and recruits the CDK9/P-TEFb complex to the viral TAR RNA in a step that links RNA polymerase II (RNAPII) C-terminal domain (CTD) Ser 2 phosphorylation with transcription elongation. Previous studies have suggested a connection ...
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| Reference Key |
jones2005genesa
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|---|---|
| Authors | Vanessa Brès, Nathan Gomes, Loni Pickle, Katherine A. Jones;Vanessa Brès;Nathan Gomes;Loni Pickle;Katherine A. Jones; |
| Journal | genes & development |
| Year | 2005 |
| DOI |
10.1101/gad.1291705
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| URL | |
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