Daratumumab plus pomalidomide and dexamethasone versus pomalidomide and dexamethasone alone in previously treated multiple myeloma (APOLLO): an open-label, randomised, phase 3 trial

National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't adult female male aged middle aged Clinical Trial Phase III Randomized Controlled Trial Antibodies Proportional Hazards Models neutropenia / chemically induced monoclonal / adverse effects neoplasm recurrence local / pathology antineoplastic combined chemotherapy protocols / adverse effects antineoplastic combined chemotherapy protocols / administration & dosage neutropenia / pathology Progression-Free Survival initials='g' affs=[] is_editor=false suffix=none equal_contrib=false) initials='j' initials='a' initials='h' initials='ma' initials='b' initials='n' initials='p' initials='l' initials='d' affs=[]) initials='s' initials='m' initials='f' initials='c' author(firstnames='philippe' author(firstnames='ali' initials='r' author(firstnames='roberto' initials='e' initials='t' author(firstnames='stefan' author(firstnames='hans' author(firstnames='mario' author(firstnames='javier' author(firstnames='xavier' initials='x' author(firstnames='juan josé' initials='jj' author(firstnames='sebastián' author(firstnames='carmen' author(firstnames='pieter' initials='mc' initials='mv' equal_contrib=false)] author(firstnames='brian' meletios a dimopoulos lastname='doyen' lastname='meuleman' lastname='wu' lastname='engelhardt' lastname='goldschmidt' lastname='knop' lastname='foa' lastname='zweegman' multiple myeloma / drug therapy* thalidomide / administration & dosage thalidomide / adverse effects thalidomide / analogs & derivatives* pmid:34087126 doi:10.1016/s1470-2045(21)00128-5 evangelos terpos collabauthor(name='apollo trial investigators' investigators=[author(firstnames='adrian' lastname='alegre amor' author(firstnames='luca' lastname='baldini' author(firstnames='meral' lastname='beksac' author(firstnames='angelo' lastname='belotti' author(firstnames='lotfi' lastname='benboubker' author(firstnames='britta' lastname='besemer' author(firstnames='sevgi' lastname='besisik' author(firstnames='jelena' lastname='bila' lastname='boccadoro' author(firstnames='michele' lastname='cavo' lastname='de la rubia comos' author(firstnames='sosana' lastname='delimpasi' author(firstnames='meletios a' lastname='dimopoulos' author(firstnames='chantal' author(firstnames='dominik' lastname='dytfeld' author(firstnames='monika' author(firstnames='thierry' lastname='facon' author(firstnames='hartmut' lastname='grosicki' author(firstnames='roman' lastname='hajek' author(firstnames='guner' lastname='hayri ozsan' author(firstnames='cyrille' lastname='hulin' lastname='iversen' author(firstnames='lionel' lastname='karlin' author(firstnames='eirini' lastname='katodritou' author(firstnames='marie-christine' lastname='kyrtsonis' lastname='lahuerta' lastname='leleu' lastname='martinez chamorro' author(firstnames='maría-victoria' lastname='mateos manteca' author(firstnames='nathalie' author(firstnames='monique' lastname='minnema' lastname='moreau' author(firstnames='massino' lastname='offidani' author(firstnames='albert' lastname='oriol rocafiguera' author(firstnames='mustafa' lastname='pehlivan' author(firstnames='ludek' lastname='pour' author(firstnames='henk th j' lastname='roerdink' initials='htj' author(firstnames='laura' lastname='rosinol dacsh' lastname='salwender' lastname='sonneveld' author(firstnames='anargyros' lastname='symeonidis' author(firstnames='charlotte' lastname='toftmann hansen' author(firstnames='tulin' lastname='tuglular' lastname='unal' author(firstnames='philip' lastname='vlummens' author(firstnames='filiz' lastname='vural' author(firstnames='ka lung' initials='kl' author(firstnames='sonja' monoclonal / administration & dosage* dexamethasone / administration & dosage* dexamethasone / adverse effects multiple myeloma / pathology local / drug therapy