Citrate anticoagulation versus systemic heparinisation in continuous venovenous hemofiltration in critically ill patients with acute kidney injury: a multi-center randomized clinical trial

National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't adult female male aged middle aged young adult 80 and over Randomized Controlled Trial Multicenter Study severity of illness index Survival Analysis intensive care units netherlands anticoagulants / adverse effects anticoagulants / therapeutic use thrombosis / etiology critical illness / therapy health care / statistics & numerical data acute kidney injury / therapy outcome and process assessment thrombosis / prevention & control* acute kidney injury / mortality initials='g' affs=[] is_editor=false suffix=none equal_contrib=false) initials='a' initials='h' initials='p' author(firstnames='g' author(firstnames='p' author(firstnames='a' affs=[]) initials='m' author(firstnames='m' equal_contrib=false)] citric acid / adverse effects citric acid / therapeutic use* pmid:25128022 pmc4161888 doi:10.1186/s13054-014-0472-6 louise schilder s azam nurmohamed collabauthor(name='cash study group' investigators=[author(firstnames='h' lastname='hart-sweet' lastname='kotsopoulos' lastname='van der weiden' lastname='kluge' lastname='rodgers' acute kidney injury / drug therapy* hemofiltration / adverse effects hemofiltration / methods* heparin / adverse effects heparin / therapeutic use* organ dysfunction scores