Real-world effectiveness and predictors of sustained virological response with all-oral therapy in 21,242 hepatitis C genotype-1 patients

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2017
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Abstract
The diversity and size of this cohort allowed for extensive examination of regimen-specific predictors of SVR. FIB-4>3.25 and detectable 4-week on-treatment HCV RNA had the greatest negative impact. African-American race, low or high BMI, and PPIs negatively impacted odds of SVR for LDV/SOF ±RBV. …
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Authors Backus LI;Belperio PS;Shahoumian TA;Loomis TP;Mole LA;;
Journal antiviral therapy
Year 2017
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/27934775
Keywords
Administration National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine prognosis treatment outcome adult female male aged middle aged Comorbidity risk factors 80 and over drug therapy combination hepatitis c / diagnosis antiviral agents / administration & dosage antiviral agents / therapeutic use* oral hepacivirus / genetics* hepatitis c / epidemiology hepatitis c / drug therapy* sustained virologic response genotype* hepatitis c / virology* lisa i backus larry a mole pmid:27934775 doi:10.3851/imp3117 pamela s belperio

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