Insulin causes fatty acid transport protein translocation and enhanced fatty acid uptake in adipocytes

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ID: 270457
2002
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Abstract
Fatty acid uptake into 3T3 L1 adipocytes is predominantly transporter mediated. Here we show that, during 3T3 L1 adipocyte differentiation, expression of fatty acid transport proteins (FATPs) 1 and 4 is induced. Using subcellular membrane fractionation and immunofluorescence microscopy, we demonstra …
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Authors Stahl A;Evans JG;Pattel S;Hirsch D;Lodish HF;;
Journal Developmental cell
Year 2002
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/11970897
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't female male P.H.S. Adipocytes / drug effects Insulin / pharmacology* Inbred BALB C adipocytes / metabolism* cell differentiation / physiology membrane transport proteins* tumor necrosis factor-alpha / pharmacology cell nucleus / metabolism carrier proteins / metabolism* hypoglycemic agents / pharmacology* antineoplastic agents / pharmacology energy metabolism / physiology pmid:11970897 doi:10.1016/s1534-5807(02)00143-0 andreas stahl james g evans harvey f lodish 3t3 cells / cytology 3t3 cells / metabolism cell membrane / metabolism fatty acid transport proteins fatty acids / pharmacokinetics*

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