A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1β Release in Response to a Pathogenic Fungus
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2018
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Abstract
The fungal pathogen P brasiliensis activates caspase-8 downstream of dectin-1 recognition leading to ASC oligomerization, caspase-1 activation, and IL-1β proces
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| Reference Key |
natália2018thea
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| Authors | Ketelut-Carneiro, Natália;Ghosh, Sreya;Levitz, Stuart M;Fitzgerald, Katherine A;da Silva, João Santana; |
| Journal | The Journal of infectious diseases |
| Year | 2018 |
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