Phosphatidylinositol 3-Kinase Signaling Does Not Activate the Wnt Cascade
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ID: 270406
2009
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Abstract
Mutational activation of the phosphatidylinositol 3-kinase (PI3K) pathway occurs in a wide variety of tumors, whereas activating Wnt pathway mutants are predominantly found in colon cancer. Because GSK3 is a key component of both pathways, it is widely ...
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| Reference Key |
clevers2009thephosphatidylinositol
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|---|---|
| Authors | Ser Sue Ng, Tokameh Mahmoudi, Esther Danenberg, Inés Bejaoui, Wim de Lau, Hendrik C. Korswagen, Mieke Schutte, Hans Clevers;Ser Sue Ng;Tokameh Mahmoudi;Esther Danenberg;Inés Bejaoui;Wim de Lau;Hendrik C. Korswagen;Mieke Schutte;Hans Clevers; |
| Journal | The Journal of biological chemistry |
| Year | 2009 |
| DOI |
10.1074/jbc.M109.078261
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| URL | |
| Keywords |
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